HEALTHY CONTROLS

This study is testing whether very gentle, barely noticeable motion can help improve balance in people with inner ear problems that affect their stability. Researchers will work with 48 participants—half with inner ear issues and half healthy—to see if this gentle motion makes ba…

This study is testing a new type of PET scan that uses much less radiation to detect and monitor neuroendocrine tumors. Researchers want to see if they can reduce the radiation dose by 10 to 100 times while still getting clear images. The trial will enroll 200 people, including b…

This study is testing whether special 'smart socks' can accurately measure walking and balance problems in people with Parkinson's disease. Researchers will compare data from 60 people—some with Parkinson's and some healthy—during a single lab visit. The goal is to see if the soc…

This study is testing a mental training technique called Graded Motor Imagery to see if it can provide immediate benefits for people with chronic ankle instability. Researchers will measure changes in pain, muscle strength, balance, and the feeling of instability in 48 participan…

This study is testing whether a single session of whole-body heat therapy, with or without a follow-up cold water plunge, can help reduce symptoms of depression. It will involve about 112 adults currently experiencing depression, who will be randomly assigned to one of the two tr…

This is a small, early-stage study to see if a personalized, non-invasive brain stimulation technique is safe and tolerable for pregnant women with depression. Researchers will test the approach on 10 participants—five healthy women and five with antenatal depression—to check for…

This study is testing a new type of brain scan to see if it can detect clumps of a specific protein linked to Parkinson's disease, Lewy body dementia, and multiple system atrophy. Researchers will give participants a small amount of a radioactive tracer and then perform a PET/MRI…

This study aims to understand why people with Lewy body dementia experience sudden, unpredictable changes in their thinking and alertness, known as cognitive fluctuations. Researchers will compare brain scans and other tests from 120 participants, including people with dementia a…

This study is testing the safety of a new, non-invasive brain stimulation technique called transcranial interference stimulation (tIS) in healthy people. The long-term goal is to see if this method could one day help treat social and emotional difficulties in people with schizoph…

This study aims to understand how low-intensity focused ultrasound affects connections between different brain regions. Researchers will apply ultrasound to specific brain pathways in 66 healthy adults and measure changes using brain scans. The goal is to gather basic knowledge a…

This study aims to understand how cocaine addiction physically changes the brain. Researchers will use special brain scans (PET and MRI) to compare the brain connections of 80 people with cocaine addiction to those of healthy volunteers. The goal is to measure differences in brai…

This study aims to understand how a supplement called HA35 affects muscle protein balance in healthy people. Participants will take either HA35 or a placebo for three days, then undergo tests including a small, controlled alcohol challenge and muscle biopsies. The goal is to gath…

This study aims to understand how people with spinal cord injuries respond to flu and COVID-19 vaccines compared to people without injuries. Researchers will measure blood markers and antibodies in 140 participants to see if injury severity affects immune protection. The goal is …

This study aims to understand how emotional states change in people with bipolar disorder compared to healthy individuals. Researchers will use brain scans (fMRI) and machine learning to see if they can identify brain activity patterns linked to mood instability. The study will a…

This study is collecting body samples like stool, saliva, and blood from 600 people to build a library for future research. The goal is to help scientists understand how the trillions of microbes living in and on our bodies affect our health and contribute to diseases. Participan…

This study aims to understand how two rare inflammatory blood vessel diseases, Takayasu arteritis and Behçet's disease, affect a person's physical strength, ability to function, and mental well-being. Researchers will compare 30 people with these conditions to healthy volunteers …