New brain scans aim to uncover why dravet patients face higher sudden death risk

NCT ID NCT07013331

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses PET and MRI scans to look at serotonin pathways in the brainstem of adults with Dravet syndrome, a severe form of epilepsy. Researchers want to see if these pathways are different in Dravet patients compared to those with other drug-resistant epilepsy and healthy people. The goal is to better understand why Dravet syndrome carries a high risk of sudden unexpected death in epilepsy (SUDEP). The study involves 30 participants: 10 with Dravet syndrome, 10 with focal epilepsy, and 10 healthy volunteers.

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Conditions

The condition(s) this trial relates to.

Dravet syndrome Drug Resistant Epilepsy Epilepsies, Myoclonic epilepsy focal epilepsy Sudden Unexpected Death in Epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Neurologique Pierre Wertheimer

    RECRUITING

    Bron, Rhone, 69500, France

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