New sedative could keep ICU patients calmer on ventilators

NCT ID NCT06575530

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study tests whether remimazolam besylate works as well as dexmedetomidine for keeping patients lightly sedated while on a breathing machine after non-cardiac surgery. About 306 adults aged 18–64 will take part across five hospitals in China. The goal is to see if remimazolam can safely provide steady sedation without causing more side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Shijitan Hospital.CMU

    RECRUITING

    Beijing, Beijing Municipality, 100038, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

remimazolam besylate

What this could lead to

If it works, this could offer a safer or equally effective sedation option for ICU patients on breathing machines after surgery.

What could go wrong

This is a Phase 4 trial, but it only compares two sedatives—not a breakthrough. Results may not apply to all ICU patients or surgeries.

Conditions

The condition(s) this trial relates to.

Critical Illness Drug-Related Side Effects and Adverse Reactions

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.