New sedative could keep ICU patients calmer on ventilators

NCT ID NCT06575530

Recruiting now Symptom relief Sponsor: Beijing Shijitan Hospital, Capital Medical University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether remimazolam besylate works as well as dexmedetomidine for keeping patients lightly sedated while on a breathing machine after non-cardiac surgery. About 306 adults aged 18–64 will take part across five hospitals in China. The goal is to see if remimazolam can safely provide steady sedation without causing more side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: remimazolam besylate
What this could lead to: If it works, this could offer a safer or equally effective sedation option for ICU patients on breathing machines after surgery.
What could go wrong: This is a Phase 4 trial, but it only compares two sedatives—not a breakthrough. Results may not apply to all ICU patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Critical Illness Drug-Related Side Effects and Adverse Reactions

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVERSE DRUG EVENT CRITICAL ILLNESS EFFECT OF DRUG MECHANICAL VENTILATION COMPLICATION SEDATION SURGERY

Contacts and locations

Locations

Beijing Shijitan Hospital.CMU
RECRUITING

Beijing, Beijing Municipality, 100038, China

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