MECHANICAL VENTILATION COMPLICATION

This study tests whether using a special lung-monitoring device (EIT) to set the ventilator during surgery can reduce lung complications like pneumonia or respiratory failure in people having laparoscopic gastric sleeve surgery. About 118 obese adults will be randomly assigned to…

This study looks at whether a drug called remazolam besylate is as good as or better than another sedative (dexmedetomidine) for keeping critically ill patients calm and comfortable while they are on a breathing machine after non-cardiac surgery. About 306 adults aged 18-64 who n…

This study looks at how common pain is in intensive care unit (ICU) patients who are on breathing machines (mechanical ventilators). Researchers will use special pain scales to check pain levels and see if pain is linked to problems like breathing trouble, longer hospital stays, …

This study compares breathing machine settings chosen by doctors with those recommended by a smartphone app called VentilO for patients just after heart surgery. The goal is to see if the app reduces the chance of respiratory acidosis (too much acid in the blood). About 76 adults…

This study looks at whether a simple measurement called the Pressure-Muscle Index (PMI) can help doctors avoid giving too much breathing support from ventilators. Too much support can weaken the diaphragm and damage the lungs. The trial involves 36 ICU patients with acute breathi…

This study looks at whether giving ICU staff real-time feedback and having a dedicated nurse facilitator can increase the use of a set of proven practices (the ABCDEF bundle) for adults on breathing machines. About 8,100 patients across multiple ICUs will take part. The goal is t…

This study looks at two ways of using a breathing machine during laparoscopic gynecologic surgery. It compares volume-controlled and pressure-controlled ventilation to see which one better protects lung function and brain oxygen levels. About 120 women aged 18-70 will take part. …

This study looks at how the diaphragm—the main breathing muscle—weakens in patients on a breathing machine (mechanical ventilation) in the ICU. Researchers will use mild nerve stimulation and ultrasound to measure muscle strength and brain control over time. The goal is to unders…

This pilot study is testing a new ultrasound technique to measure how the lungs move and stretch in patients on breathing machines in the intensive care unit. The goal is to collect data that could help doctors better understand and prevent lung injury caused by mechanical ventil…