New device settings may help ventilator patients breathe easier

NCT ID NCT06491017

Recruiting now Symptom relief Sponsor: Hospital Clinic of Barcelona Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether using a special cough-assist device (MI-E) with optimized settings can remove more mucus from the airways of critically ill patients on breathing machines. Researchers will compare the amount of mucus suctioned after using optimized versus standard settings in 26 adults. The goal is to find the best way to clear secretions and prevent complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mechanical insufflator-exsufflator (MI-E) device
What this could lead to: If it works, this could lead to better mucus clearance guidelines for ventilated patients, reducing complications like infections.
What could go wrong: This is a small, early-phase study with only 26 participants, so results may not apply broadly. The intervention is a device setting change, not a new drug, so the impact is limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

mucocele of salivary gland

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MECHANICAL VENTILATION COMPLICATION MUCUS RETENTION

Contacts and locations

Locations

Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain

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