Ultrasound could reveal hidden diaphragm weakness in ventilator patients

NCT ID NCT03129217

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether a specific ultrasound measurement—called maximal diaphragm thickening fraction—can accurately assess diaphragm function in patients who are on mechanical ventilation. Researchers will compare this ultrasound technique to a standard method (phrenic nerve stimulation) in adults who are ready to try breathing on their own. If validated, this non-invasive approach could help doctors better predict when patients can safely be taken off the ventilator.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could provide a simple, non-invasive way to assess diaphragm strength in ventilated patients, helping doctors decide when to remove breathing support.

What could go wrong

This is a small, early-stage study focused on validating a measurement technique. It may not translate into better patient outcomes or apply to all ventilator patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Health Network

    Toronto, Ontario, M5G 2N2, Canada