New study reveals hidden damage from ventilators

NCT ID NCT03108118

First seen Jun 23, 2026 · Last updated Jun 23, 2026

Summary

This study looks at how the diaphragm—the main muscle used for breathing—gets injured in patients who need a breathing machine. Researchers followed 50 critically ill adults for up to 7 days, measuring muscle activity and function. The goal is to understand why this injury happens and how to prevent it in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mount Sinai Hospital

    Toronto, Ontario, M5G 1X5, Canada

  • University Health Network

    Toronto, Ontario, M5G 2N2, Canada

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors better understand how to prevent diaphragm injury in patients on breathing machines.

What could go wrong

This is a small observational study with only 50 participants, so findings may not apply to all patients. It does not test any treatment.

Conditions

The condition(s) this trial relates to.

Respiratory Insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.