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Which ventilator mode helps patients breathe on their own sooner?

NCT ID NCT03901924

Recruiting now Disease control Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study compares two ways of using a breathing machine (mechanical ventilator) in adults who need help breathing. One mode lets the patient trigger each breath, while the other delivers a set number of breaths regardless of patient effort. The goal is to see which approach leads to more days off the ventilator and less thinning of the diaphragm muscle. The results could guide how ventilators are used in intensive care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mechanical ventilation modes (volume support and assist control)
What this could lead to
If one mode proves better, it could become the standard approach to help patients on ventilators recover faster and preserve diaphragm strength.
What could go wrong
This is a single trial, and results may not apply to all patient groups. Both modes are already in use, so the difference may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MECHANICAL VENTILATION COMPLICATION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Chicago Medical Center

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Iowa

    NOT_YET_RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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