Nanfang Hospital, Southern Medical University

This study tests whether adding a new targeted drug to standard chemotherapy helps adults with newly diagnosed acute T-lymphocytic leukemia live longer. About 154 participants will be randomly assigned to get either the new combo or chemo alone. The main goal is to see if the com…

This study looks at 246 people who need a tooth repaired after a root canal. It compares two methods: a modified endocrown (a single-piece cap) versus a post and core with a full crown (a two-piece option). The goal is to see which restoration survives better over two years, help…

This study tests whether combining platelet-rich plasma (PRP) with Botox injections works better than PRP alone for treating male and female pattern baldness. About 76 adults aged 18 to 60 will receive monthly scalp injections for three months. Researchers will track hair density…

This study tests a new procedure using an ultrasound scope to disconnect stomach varices (enlarged veins) and prevent them from bleeding again. It compares this method to the standard glue injection. About 84 people with high-risk stomach varices will be randomly assigned to one …

This study is testing a three-part treatment for advanced liver cancer that has spread into a major vein in the liver. The treatment combines immunotherapy (QL1706), a drug that blocks tumor blood supply (bevacizumab), and chemotherapy delivered directly into the liver's artery. …

This study is testing whether artificial intelligence (AI) can accurately predict important molecular changes in gliomas, a type of brain tumor, by analyzing digital pathology images. Researchers will compare the AI's predictions against standard laboratory test results from 2,00…

This study compares two sedatives, ciprofol and propofol, in ICU patients who need breathing support but are not on a ventilator. The goal is to see which drug works better and causes fewer breathing problems. About 1,680 adults from 30 hospitals in China will be included, and re…

This study looks at why people with chronic kidney disease (CKD) often lose muscle mass and strength, a condition called sarcopenia. Researchers will follow 1,000 adults with CKD to find risk factors for sarcopenia and see how it affects their health over time. The goal is to bet…

This study looks at liver tissue and blood from 240 people with various liver conditions, including fatty liver, hepatitis B, fibrosis, and cirrhosis. Researchers will use advanced cell analysis to map how liver cells change and interact as disease progresses. The goal is to find…

This study follows 800 adults with type 2 diabetes to see how their lifestyle choices relate to long-term complications like heart or kidney problems. Researchers will track participants over time and record any complications that develop. The goal is to find early warning signs …

This study looks at how common sleep apnea is in people with chronic kidney disease (CKD) and whether it makes kidney function worse over time. Researchers will follow 356 adults with moderate to severe CKD who are not on dialysis. The goal is to find risk factors for sleep apnea…

This study looks at how immune cells in special areas called germinal centers work in people with long-term hepatitis B. Researchers will collect blood and leftover tissue from surgeries to study these immune responses. The goal is to better understand the disease, not to test a …

This study looks back at medical records of 1500 adults in the ICU with sepsis and low platelet counts. Researchers want to see if giving platelet transfusions helps patients survive for 28 days. The goal is to understand if this common treatment is helpful or harmful.

This observational study follows 5,000 untreated chronic hepatitis B patients aged 1 to 80 for years. Researchers will test blood every six months to see how the immune system changes as the disease progresses. The goal is to understand the role of age and immune response in the …

This study looks at 3,000 people with type 2 diabetes to see if signs of inflammation in the blood can predict complications like heart or kidney problems. Researchers will review medical records from a hospital in China. The goal is to find early warning signs and identify high-…