Nanfang Hospital, Southern Medical University

This study is comparing two different ways to fix and protect a tooth that has had a large filling or defect after a root canal. Researchers will test a newer method called a 'modified endocrown' against the more traditional method of using a post, core, and full crown. They will…

This study is testing whether the drug anlotinib can help control recurrent craniopharyngioma, a type of brain tumor that has come back after previous treatment. It will enroll about 57 adults to see if the drug shrinks tumors, delays tumor growth, and is safe to use. The trial i…

This study is testing a new three-part treatment for people with advanced liver cancer that has spread into a major vein in the liver. The treatment combines immunotherapy, a targeted drug, and chemotherapy delivered directly to the liver. The main goal is to see if this combinat…

This study is testing whether adding new targeted drugs to standard chemotherapy works better than chemotherapy alone for adults newly diagnosed with a fast-growing blood cancer called acute T-lymphocytic leukemia. About 154 patients will be randomly assigned to receive either th…

This study is testing a new way to create detailed 3D pictures of lung and colon cancer tumors from patient tissue samples. Researchers will use a special process to make the tissue clear and then stain it with fluorescent dyes to see its full 3D structure. The goal is to help do…

This study is testing whether an artificial intelligence (AI) tool can accurately predict important genetic changes in a type of brain tumor called glioma, using standard microscope images. Researchers will compare the AI's predictions against traditional, more expensive lab test…

This study is testing a new artificial intelligence (AI) tool designed to help pathologists diagnose cancer. The AI analyzes images of tissue samples to see if it can accurately identify and classify different cancers. The goal is to make cancer diagnosis faster and more reliable…

This study is testing a new fluorescent imaging probe designed to help surgeons see if early stomach cancer has spread to nearby lymph nodes during surgery. The goal is to accurately tell the difference between healthy and cancerous lymph nodes so that only the affected ones are …

This is an observational study that aims to learn how the body's immune system changes as people live with chronic Hepatitis B over many years. Researchers will follow 5,000 untreated patients, aged 1 to 80, checking their blood every six months to see how their immune cells resp…

This study aims to find out if giving platelet transfusions to intensive care patients with sepsis and low platelet counts helps them survive or causes more harm. Researchers will look back at the medical records of 1,500 patients to see if those who received transfusions had bet…

This study aims to understand how various liver conditions, like fatty liver disease, hepatitis B, and liver scarring, develop and progress. Researchers will analyze blood and small pieces of leftover liver tissue from 240 patients who are already having surgery or a biopsy for t…

This study aims to understand how the immune system responds to chronic Hepatitis B virus (HBV) infection. Researchers will collect and analyze blood and tissue samples from 280 people with and without chronic HBV who are already scheduled for certain surgeries. The goal is to le…

This study aims to understand how common obstructive sleep apnea is in people with chronic kidney disease (CKD) and whether having sleep apnea makes kidney disease worse over time. Researchers will follow 356 adults with moderate CKD for a long period to identify risk factors and…

This study aims to understand if a patient's emotional state affects how well they respond to a specific combination treatment for advanced liver cancer. Researchers will observe 90 patients receiving standard therapy, grouping them by their mood scores, and track their health ou…