Could a single surgery replace daily eye drops for glaucoma?

NCT ID NCT07700498

Recruiting now Disease control Sponsor: Nanfang Hospital, Southern Medical University Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial tests whether combining cataract surgery with a procedure called gonioscopy-assisted trabeculotomy (GAT) can reduce the need for long-term glaucoma eye drops in adults with both primary open-angle glaucoma and cataracts. Participants will either receive the combined surgery or cataract surgery followed by standard eye drops. The study tracks eye pressure, eye surface health, and quality of life over 24 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: phacoemulsification combined with gonioscopy-assisted trabeculotomy
What this could lead to: If successful, this approach could reduce or eliminate the need for daily glaucoma eye drops, improving quality of life and eye surface health.
What could go wrong: This is a relatively small trial, and the surgery carries risks like infection or inflammation. It may not work for everyone, and long-term benefits are still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cataract open-angle glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRIMARY OPEN ANGLE GLAUCOMA AND CATARACTS

Contacts and locations

Locations

Nanfang Hospital, Southern Medical University
RECRUITING

Guangzhou, China
People's Hospital of Ningxia Hui Autonomous Region
NOT_YET_RECRUITING

Ningxia, Ningxia, China
The Affiliated Hospital of Southwest Medical University
NOT_YET_RECRUITING

Luzhou, China
The First Affiliated Hospital of Zhengzhou University
NOT_YET_RECRUITING

Zhengzhou, China
Zhuhai Hospital of Guangdong Provincial Hospital of Chinese Medicine
NOT_YET_RECRUITING

Zhuhai, China