Brain aneurysm showdown: which procedure is safer?
NCT ID NCT07707076
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This trial compares two endovascular procedures for treating unruptured wide-neck brain aneurysms: a flow diverter device (Pipeline) versus traditional stent-assisted coiling. About 266 adults aged 18–75 with these aneurysms will be randomly assigned to one treatment and followed for up to 5 years. The goal is to see which approach has fewer complications like stroke or death, and which leads to better long-term aneurysm closure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a flow diverter device (Pipeline) or a stent-assisted coiling procedure
- What this could lead to
- If one approach proves safer and more effective, it could become the preferred treatment for these hard-to-treat brain aneurysms, reducing stroke risk and improving long-term outcomes.
- What could go wrong
- This is a randomized trial, but results may not apply to all aneurysm types or patients. Both procedures carry risks like stroke or vessel damage, and long-term benefits are still being studied.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Nanfang Hospital, Southern Medical University
RECRUITINGGuangzhou, Guangdong, 510515, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••