New dissolving plate could stop brain fluid leaks after nose surgery

NCT ID NCT07539792

Recruiting now Disease control Sponsor: Nanfang Hospital, Southern Medical University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a special plate that dissolves over time, placed during nose surgery to remove pituitary tumors. The plate supports the skull base to prevent spinal fluid leaks, a common complication. About 126 people aged 1 to 80 with sellar tumors will be randomly assigned to get the plate or standard care. The main goal is to see if the plate reduces fluid leaks within the first month after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: absorbable and moldable skull base support plate (device)
What this could lead to: If it works, this could reduce the risk of spinal fluid leaks and infections after pituitary tumor surgery, leading to faster recovery and shorter hospital stays.
What could go wrong: This is a Phase 2 trial with only 126 participants, so results may not apply to all patients. The plate is new and could cause nasal complications or fail to prevent leaks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CSF LEAKAGE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cerebrospinal fluid leak cerebrospinal fluid rhinorrhea sella turcica neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CSF LEAKAGE ENDONASAL SURGERY SELLAR TUMOR

Contacts and locations

Locations

Gaozhou People's Hospital
NOT_YET_RECRUITING

Gaozhou, Guangdong, China
Guangdong Provincial Hospital of Traditional Chinese Medicine
NOT_YET_RECRUITING

Guangzhou, Guangdong, China
Huizhou Central People's Hospital
NOT_YET_RECRUITING

Huizhou, Guangdong, China
Liuzhou people's hospital
NOT_YET_RECRUITING

Liuzhou, Guangxi, China
Southern Medical University, Nanfang Hospital, Department of Neurosurgery
RECRUITING

Guangzhou, Guangdong, 510515, China
Sun Yat-sen University Cancer Center
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510060, China
The First People's Hospital Of Foshan
NOT_YET_RECRUITING

Foshan, Guangdong, China
The First People's Hospital of Zhaoqing
NOT_YET_RECRUITING

Zhaoqing, Guangdong, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.