New dissolving plate could stop brain fluid leaks after nose surgery

NCT ID NCT07539792

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a special plate that dissolves over time, placed during nose surgery to remove pituitary tumors. The plate supports the skull base to prevent spinal fluid leaks, a common complication. About 126 people aged 1 to 80 with sellar tumors will be randomly assigned to get the plate or standard care. The main goal is to see if the plate reduces fluid leaks within the first month after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

absorbable and moldable skull base support plate (device)

What this could lead to

If it works, this could reduce the risk of spinal fluid leaks and infections after pituitary tumor surgery, leading to faster recovery and shorter hospital stays.

What could go wrong

This is a Phase 2 trial with only 126 participants, so results may not apply to all patients. The plate is new and could cause nasal complications or fail to prevent leaks.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ENDONASAL SURGERY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cerebrospinal fluid leak cerebrospinal fluid rhinorrhea sella turcica neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gaozhou People's Hospital

    NOT_YET_RECRUITING

    Gaozhou, Guangdong, China

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-••••

    Contact

  • Guangdong Provincial Hospital of Traditional Chinese Medicine

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Huizhou Central People's Hospital

    NOT_YET_RECRUITING

    Huizhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Liuzhou people's hospital

    NOT_YET_RECRUITING

    Liuzhou, Guangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Southern Medical University, Nanfang Hospital, Department of Neurosurgery

    RECRUITING

    Guangzhou, Guangdong, 510515, China

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact

  • Sun Yat-sen University Cancer Center

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First People's Hospital Of Foshan

    NOT_YET_RECRUITING

    Foshan, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First People's Hospital of Zhaoqing

    NOT_YET_RECRUITING

    Zhaoqing, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact