Which scope technique wins for tiny rectal tumors?
NCT ID NCT07759960
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This trial compares two minimally invasive endoscopic procedures—underwater endoscopic mucosal resection (UEMR) and endoscopic submucosal dissection (ESD)—for removing small rectal neuroendocrine tumors (NETs) that are 10 mm or smaller. The goal is to see if UEMR is as effective as ESD in completely removing the tumor in one piece, while also evaluating safety and procedure time. Adults aged 18 to 75 with suspected or confirmed small rectal NETs may participate. The findings could help doctors choose the best technique for this condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Two endoscopic procedures: underwater endoscopic mucosal resection (UEMR) and endoscopic submucosal dissection (ESD)
- What this could lead to
- If one technique proves superior, it could become the preferred standard for removing small rectal neuroendocrine tumors, improving outcomes and reducing complications.
- What could go wrong
- This is a non-inferiority trial, so it may show the two methods are similar rather than one being better. Results may not apply to larger tumors or other patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Nanfang Hospital, Southern Medical University
RECRUITINGGuangzhou, Guangdong, 510515, China