Nanfang Hospital, Southern Medical University

This phase 2 trial tests a combination of two drugs (donafenib and sintilimab) plus a procedure called TACE in 48 adults with advanced liver cancer that cannot be surgically removed. The goal is to see if this triple therapy can shrink tumors and control the disease. The study is…

This study tests a blood-filtering treatment called DPMAS for people with severe liver failure. The goal is to see if it can lower the risk of death or worsening disease within weeks. About 1300 adults with chronic liver disease and high bilirubin levels are taking part. Research…

This study aimed to see if a special type of stem cell (hAESC) could safely prevent acute graft-versus-host disease in people receiving a stem cell transplant for blood cancer. It was designed for adults at high risk of this complication. However, the study was withdrawn before a…

This study looks at whether a three-part treatment—blocking the tumor's blood supply (TACE), precise radiation (SBRT), and drugs that boost the immune system—can help people with intermediate to advanced liver cancer that cannot be removed by surgery. The 17 participants all rece…

This study is developing and testing an AI model that automatically interprets CLDN18.2 protein levels in digestive system tumors. Researchers will use thousands of pathology samples from multiple hospitals to see if the AI can read test results as accurately as human experts. Th…

This study is testing a new artificial intelligence (AI) system that combines information from tissue samples, scans, and medical records to help doctors better diagnose and treat cancer. Researchers will enroll 2000 adults with various cancers to see how well the AI can classify…

This study uses artificial intelligence to analyze pathology slides and medical images from 2000 adults with various cancers. The goal is to help doctors more accurately classify tumors, predict treatment responses, and personalize care. Participants must be 18-75 and have comple…

This study tests a new sedative called remimazolam for people in the ICU who need a breathing tube after oral or facial surgery. It compares remimazolam to two standard sedatives, propofol and midazolam, to see if it works just as well and helps patients wake up faster. The trial…

This study looks at 80 patients with both locally advanced gastric cancer and high blood pressure. Researchers want to see if taking beta-blockers (a common blood pressure drug) alongside standard cancer treatment leads to better tumor shrinkage compared to other blood pressure d…

This study uses an AI model to analyze patient data and recommend the best follow-up treatment after surgery for advanced head and neck cancer. Researchers will track 571 patients over two years to see if the AI's suggestions improve survival and reduce recurrence. The goal is to…

This study reviewed medical records of 500 adults with esophageal cancer treated between 2017 and 2024. Researchers analyzed patient details, lab results, tumor information, and treatments to find factors that influence survival. No new treatments were tested; the goal was to lea…

This study tests whether an artificial intelligence (AI) model can help pathologists diagnose gastric cancer more accurately and quickly. About 1000 patients with gastric biopsies or surgical samples will take part. Some pathologists will use the AI tool to assist their diagnosis…