New blood filter shows promise for liver failure patients

NCT ID NCT05129904

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a blood-filtering treatment called DPMAS for people with severe liver failure. The goal is to see if it can lower the risk of death or worsening disease within weeks. About 1300 adults with chronic liver disease and high bilirubin levels are taking part. Researchers will also collect blood, urine, and stool samples to better understand who benefits most.

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Conditions

The condition(s) this trial relates to.

Acute-On-Chronic Liver Failure liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Ditan Hospital, Capital Medical University

    Beijing, China

  • Beijing Youan Hospital, Capital Medical University

    Beijing, China

  • Chengdu Public Health Clinical Center

    Chengdu, China

  • First Affiliated Hospital of Anhui Medical University

    Hefei, China

  • First Affiliated Hospital of Fujian Medical University

    Fujian, China

  • General Hospital of Ningxia Medical University

    Qinghai, China

  • Guizhou Provincial People's Hospital

    Guizhou, China

  • Hainan Provincial People's Hospital

    Hainan, China

  • Henan Provincial People's Hospital

    Henan, China

  • Huashan Hospital, Fudan University

    Shanghai, China

  • Hunan Provincial People's Hospital

    Changsha, Hunan, China

  • Infectious Diseases Hospital Affiliated to Nanchang University

    Nanchang, China

  • Luhe Hospital, Capital Medical University

    Beijing, China

  • Mengchao Hepatobiliary Hospital of Fujian Medical University

    Fujian, China

  • Nanfang Hospital

    Guangzhou, Guangdong, 510515, China

  • Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School

    Nanjing, Jiangsu, China

  • Peking University People's Hospital

    Beijing, China

  • Qilu Hospital of Shandong University

    Jinan, Shandong, China

  • Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

    Shanghai, China

  • Shandong Provincial Clinical Center for Public Health

    Jinan, Shandong, China

  • Shanghai Jiao Tong University Affiliated Sixth People's Hospital

    Shanghai, China

  • Shanghai Public Health Clinical Centre

    Shanghai, China

  • Shanghai Public Health Clinical Centre, Fudan University

    Shanghai, China

  • Sichuan Provincial People's Hospital

    Chengdu, Sichuan, China

  • Southwest Hospital, Third Military Medical University

    Chongqing, China

  • Taihe Hospital, Hubei University of Medicine

    Hubei, China

  • The Affiliated Hospital of Guizhou Medical University

    Guizhou, China

  • The Affiliated Hospital of Xuzhou Medical University

    Xuzhou, Jiangsu, China

  • The Affiliated Hospital of Zunyi Medical University

    Guizhou, China

  • The First Affiliated Hospital of Guangxi Medical University

    Guangxi, China

  • The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine

    Guangxi, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, China

  • The First Affiliated Hospital of Shandong First Medical University

    Jinan, Shandong, China

  • The First Affiliated Hospital of Shanxi Medical University

    Shanxi, China

  • The First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, China

  • The First Affiliated Hospital of Xinjiang Medical University

    Xinjiang, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, China

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    Zhejiang, China

  • The First Hospital of Jilin University

    Changchun, Jilin, China

  • The First Hospital of Lanzhou University

    Lanzhou, China

  • The First Hospital of Yunnan Province

    Kunming, Yunnan, China

  • The First People's Hospital of Foshan

    Foshan, China

  • The People's Hospital of Guangxi Zhuang Autonomous Region

    Guangxi, China

  • The Second Affiliated Hospital Of Nanchang University

    Nanchang, Jiangxi, China

  • The Second Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China

  • The Second Affiliated Hospital of Guangxi Medical University

    Guangxi, China

  • The Second Affiliated Hospital of Kunming Medical University

    Kunming, China

  • The Second Hospital of Hebei Medical University

    Hebei, China

  • The Second Hospital of Shandong University

    Jinan, Shandong, China

  • The Second Xiangya Hospital, Central South University

    Changsha, China

  • The Third Hospital of Hebei Medical University

    Hebei, Hebei, China

  • Tianjin Third Central Hospital

    Tianjin, China

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Hubei, China

  • West China Hospital of Sichuan University

    Chengdu, Sichuan, China

  • Xiangya Hospital of Central South University

    Changsha, Hunan, China

  • Zhengzhou University Affiliated Luoyang Centre Hospital

    Luoyang, China