Promising combo targets rare leukemia without prior treatment
NCT ID NCT03410875
First seen Feb 24, 2026 · Last updated May 08, 2026 · Updated 13 times
Summary
This study tests two drugs, vemurafenib (a pill) and obinutuzumab (an infusion), in 30 people with untreated hairy cell leukemia. The goal is to see if the combination can achieve a complete response, meaning no signs of cancer after treatment. Participants take vemurafenib for 4 months and receive obinutuzumab infusions starting in the second month. This is an early-phase trial to check effectiveness and safety.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10021, United States
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Memorial Sloan Kettering Cancer Center @ Commack (Limited Protocol Activities)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, 10604, United States
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Memorial Sloan Kettering at Basking Ridge
Basking Ridge, New Jersey, 07920, United States
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Yale University
New Haven, Connecticut, 06511, United States
Conditions
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