New drug combo shows promise in fighting esophageal cancer

NCT ID NCT02962063

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 22 times

Summary

This study tests the safety of adding two immunotherapy drugs, durvalumab and tremelimumab, to standard chemotherapy and radiation for people with esophageal or gastroesophageal junction cancer. About 64 participants will receive initial chemotherapy followed by the drug combo with radiation. The goal is to see if this approach improves cancer control without causing severe side effects.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Rockville Centre

    Rockville Centre, New York, 11570, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.