Supercharged immune cells take on childhood leukemia

NCT ID NCT01860937

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tests the safety of giving patients their own genetically modified T-cells to fight relapsed B-cell acute lymphoblastic leukemia. The study includes children and young adults up to age 26 whose leukemia has returned or is hard to treat. The modified T-cells are designed to target and destroy cancer cells, with the goal of finding a safe dose.

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Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia Burkitt lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dana-Farber Cancer Institute:Dana- Farber/Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States