Could a liver artery shot make cancer treatment more effective?

NCT ID NCT04544098

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests whether giving the drug Lutathera directly into the liver artery is safe and practical for people with neuroendocrine tumors that have spread mainly to the liver. Ten participants will receive two doses into the liver artery followed by two standard IV doses. Researchers will compare the two methods and check if the tumors shrink.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lutathera (177Lu-DOTATATE)

What this could lead to

If this works, it could show a new way to deliver Lutathera that is more effective for liver tumors, potentially improving control of neuroendocrine cancer that has spread to the liver.

What could go wrong

This is a very early, small pilot study with only 10 people, so results may not apply widely. The treatment involves radiation and may cause side effects like liver damage or low blood counts.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bronchial endocrine tumor digestive system neuroendocrine tumor, grade 1/2 neuroendocrine neoplasm pancreatic neuroendocrine neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States