Can a simple drug tame CAR-T's dangerous side effects?
NCT ID NCT04148430
First seen Nov 06, 2025 · Last updated May 07, 2026 · Updated 22 times
Summary
This study tests whether the drug anakinra can prevent or reverse severe side effects from CAR-T cell therapy, a powerful cancer treatment. About 62 adults with certain B-cell cancers (like leukemia or lymphoma) will receive anakinra alongside their CAR-T cells. The goal is to reduce serious nervous system problems and cytokine release syndrome, making the treatment safer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hackensack Meridian Health (Data collection only)
Hackensack, New Jersey, 07601, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
Conditions
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