Fitness test could guide safer stem cell transplants for seniors
NCT ID NCT04761770
First seen Feb 28, 2026 · Last updated Jun 23, 2026 · Updated 14 times
Summary
This study tests whether a geriatric assessment—looking at thinking, mobility, mood, nutrition, and medications—can help doctors choose the right transplant intensity for patients aged 60 and older with myeloid blood cancers. The goal is to reduce deaths from transplant complications and improve quality of life. Thirty-three participants will receive a stem cell transplant with a conditioning regimen tailored to their frailty level.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Memorial Sloan Kettering Basking Ridge (Consent Only)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (Consent Only)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack (Consent only)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (Consent Only)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (Consent Only)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester (Consent Only)
Harrison, New York, 10604, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
geriatric assessment and risk-adapted conditioning regimen
What this could lead to
If successful, this approach could help doctors personalize transplant intensity for older patients, potentially reducing deaths from transplant complications and improving quality of life.
What could go wrong
This is a small, early-phase study (33 participants) without a control group, so results may not apply broadly. The geriatric assessment may not reliably predict outcomes, and transplant still carries serious risks like infection and graft-versus-host disease.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.