Personalized vaccine shows promise in pancreatic cancer trial
NCT ID NCT04161755
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial is testing whether a personalized cancer vaccine, combined with an immunotherapy drug (atezolizumab) and chemotherapy, is safe for people with pancreatic cancer that has been surgically removed. The vaccine is made specifically for each patient based on their tumor's unique features. The study involves 29 participants and aims to see if this combination can help prevent the cancer from returning.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
personalized cancer vaccine (RO7198457) and atezolizumab
What this could lead to
If this works, it could point toward a new way to prevent pancreatic cancer from coming back after surgery.
What could go wrong
This is a very early phase 1 trial with only 29 people, so it is mainly checking safety. The vaccine is personalized, which makes it complex and expensive, and it may not work for everyone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (All Protocol Activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Cancer Center @ Commack (All Protocol Activities)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (All Protocol Activities)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (All Protocol Activities)
Rockville Centre, New York, 11570, United States
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Memorial Sloan Kettering Westchester (All Protocol Activities)
Harrison, New York, 10604, United States