Can a common painkiller stop brain tumors? new study hopes to find out
NCT ID NCT02429570
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests meclofenamate, a drug once used for pain, in 30 patients with brain metastases that have come back or grown despite prior treatments. The goal is to see if the drug can prevent new brain metastases and whether a larger trial is feasible. Researchers will monitor MRI scans and side effects to decide next steps.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Meclofenamate (a pain drug repurposed to prevent new brain metastases)
What this could lead to
If it works, this could point toward a new way to slow or prevent brain metastases from growing, offering more time for patients.
What could go wrong
This is a very early pilot study with only 30 people. It is designed mainly to see if a larger trial is possible, not to prove effectiveness. The drug may not work or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Baptist Health South Florida
Miami, Florida, 33143, United States
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Lehigh Valley Health Network
Allentown, Pennsylvania, 18103, United States
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Memorial Sloan Kettering Cancer Center
Basking Ridge, New Jersey, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Cancer Center at Commack
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Westchester
Harrison, New York, 10604, United States