New drug combo shows promise for tough pancreatic cancer

NCT ID NCT04666740

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests whether combining two drugs, pembrolizumab (which helps the immune system fight cancer) and olaparib (which stops cancer cells from repairing themselves), can help people with metastatic pancreatic cancer that has a specific genetic feature or has responded well to platinum chemotherapy. The trial enrolls 63 adults whose disease is stable or improving on current platinum treatment. The goal is to see if this combination works better than olaparib alone in keeping the cancer from growing.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (All protocol activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Bergen (All protocol activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (All protocol activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth (All protocol activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (All protocol activities)

    Rockville Centre, New York, 11553, United States

  • Memorial Sloan Kettering Westchester (All Protocol Activities)

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.