Could a breast cancer drug help fight liposarcoma?

NCT ID NCT02846987

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called abemaciclib in 33 people with dedifferentiated liposarcoma, a rare soft tissue cancer that has spread or cannot be removed by surgery. The drug aims to slow tumor growth or shrink it by at least a quarter. Abemaciclib is not yet approved for this cancer, but has shown promise in other cancers like breast and lung cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Abemaciclib (a targeted cancer drug)

What this could lead to

If it works, this could offer a new treatment option for people with dedifferentiated liposarcoma that has spread or come back.

What could go wrong

This is an early Phase 2 trial with only 33 people. Abemaciclib has not been tested in liposarcoma before, so it may not work or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dedifferentiated liposarcoma liposarcoma sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States