CLL breakthrough: shorter treatment may be safer and just as effective
NCT ID NCT04722172
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) can safely stop taking acalabrutinib and obinutuzumab once their cancer responds very well, instead of continuing treatment indefinitely. The goal is to reduce serious side effects and prevent drug resistance. About 55 participants will receive the drugs and then be monitored closely after stopping treatment.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hackensack Meridian Health (Data collection only)
Hackensack, New Jersey, 07601, United States
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Memorial Sloan Kettering Basking Ridge (All protocol activities)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (All protocol activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack (All protocol activities)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (All protocol activities)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (All protocol activities)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester (All protocol activities)
Harrison, New York, 10604, United States