New drug combo aims to shrink plasma cell tumors

NCT ID NCT04174196

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether combining two drugs (lenalidomide and CC-486) with radiation therapy is safe and works well for people with plasmacytoma, a tumor made of plasma cells. About 21 adults with newly diagnosed or returning plasmacytoma will take part. The main goal is to see if the tumor disappears completely after 6 treatment cycles.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma plasmacytoma primary plasmacytoma of the bone solitary osseous plasmacytoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center @ Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States