Could fewer immunotherapy doses work for some melanoma patients? new study investigates.
NCT ID NCT03122522
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a personalized approach to dosing two immunotherapy drugs (ipilimumab and nivolumab) for people with advanced melanoma. Instead of giving everyone four doses, doctors will check after two doses: patients who show early benefit may stop, while those who don't can receive extra doses. The goal is to see if this flexible plan works as well as the standard fixed schedule.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital (Data and Specimen Analysis Only)
Boston, Massachusetts, 02115, United States
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Columbia University (Data Analysis Only)
New York, New York, 10032, United States
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Hartford Healthcare Alliance (Data Collection Only)
Hartford, Connecticut, 06102, United States
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Hospital for Special Surgery (Data Analysis)
New York, New York, 10021, United States
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JOHNS HOPKINS HOSPITAL (Data Analysis Only)
Baltimore, Maryland, 21287, United States
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Jaykumar Thumar
Hartford, Connecticut, 06102, United States
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Lehigh Valley Health Network (Data Collection Only)
Allentown, Pennsylvania, 18103, United States
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Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester
Harrison, New York, 10604, United States