Can a single drug make stem cell recovery less miserable for older patients?

NCT ID NCT03315026

First seen Nov 04, 2025 · Last updated Apr 28, 2026 · Updated 30 times

Summary

This study looks at whether giving siltuximab before and after an autologous stem cell transplant can reduce common side effects like fatigue, pain, and nausea in patients aged 60-75 with multiple myeloma or AL amyloidosis. The drug blocks a protein called IL-6 that is linked to inflammation and worse symptoms after transplant. The goal is to help patients feel better and recover faster, potentially shortening hospital stays.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.