New drug aims to reduce pain and fatigue after stem cell transplant in older patients

NCT ID NCT03315026

First seen Nov 04, 2025 · Last updated Jun 15, 2026 · Updated 36 times

Summary

This study tests whether a drug called siltuximab can reduce symptoms like weakness, fatigue, nausea, and pain after a stem cell transplant in patients aged 60-75 with multiple myeloma or AL amyloidosis. The drug blocks a protein linked to inflammation, which may help patients recover faster and spend less time in the hospital. About 30 participants will receive siltuximab before and after their transplant to see if it improves their quality of life.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.