New PET tracer could light up brain tumors

NCT ID NCT03465618

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 1 study tests a new PET imaging tracer called 89Zr-cRGDY in 17 people with malignant brain tumors or pituitary adenomas. The tracer is given in a very small dose to see how it spreads and clears from the body. The goal is to improve brain tumor imaging, not to treat the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
89Zr-DFO-cRGDY-PEG-Cy5-C' dots (ultrasmall silica particle tracer)
What this could lead to
If successful, this imaging method could help doctors see brain tumors more clearly, potentially guiding future treatments.
What could go wrong
This is a very early, small study (17 people) testing a new tracer for the first time in humans. It is not designed to treat or cure cancer, and the tracer may not work as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

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Other studies related to the condition(s) this trial covers.