BRAIN CANCER

This early-stage study is testing a new combination treatment for adults with aggressive brain cancer that has returned after prior therapy. After surgeons remove as much tumor as possible, a modified virus is injected into the area to target remaining cancer cells. The main goal…

This study is testing whether adding the drug ruxolitinib to the standard treatment (radiation plus temozolomide) works better for people newly diagnosed with glioblastoma, a serious type of brain cancer. About 190 adults will be randomly assigned to receive either the standard t…

This study aims to find out if the cancer drug trastuzumab deruxtecan (T-DXd) can get into brain tumors when given through an IV. Researchers will measure how much of the drug reaches the tumor during surgery in 30 adults with certain HER2-positive brain cancers or recurrent glio…

This study is testing whether a new type of PET scan, using a tracer called 18F-Fluciclovine, can help doctors see leftover or returning brain cancer cells more clearly after surgery. It aims to improve how doctors plan follow-up radiation treatment by finding tumor areas that a …

This study is testing a new blood test designed to detect many types of cancer early, before symptoms appear. It will involve 7,000 people, both with and without cancer, to see if the test can accurately spot cancer signals and identify where in the body the cancer started. The t…

This study is testing a home-based program called HOBSCOTCH-CA, designed to help brain cancer survivors manage memory and thinking problems that often follow their illness. Participants will work one-on-one with a coach over video calls to learn problem-solving and relaxation tec…

This study is testing whether advanced MRI scans can better identify which areas of a malignant brain tumor are most likely to grow back after standard treatment. Researchers will enroll adults with glioma to see if these detailed images can safely help guide future radiation the…

This large international study is collecting information on a new, more precise type of radiation therapy that uses real-time MRI scans to guide treatment. It aims to see if this advanced technology helps people with many types of cancer live longer, better control their tumors, …

This study is testing whether a new type of imaging scan, called an 18F-fluciclovine PET/CT, can better show if radiation treatment is working for large brain tumors that have spread from cancer elsewhere in the body. Researchers will enroll 20 adults with these large brain metas…

This study is testing a new technology called SmartMatch that analyzes small pieces of surgically removed brain tumor tissue to see how they react to different drugs. Researchers want to see if this analysis can be completed and a report provided to doctors within 21 days of surg…