New drug targets deadly brain cancer that has returned

NCT ID NCT07416188

First seen Feb 22, 2026 · Last updated May 02, 2026 · Updated 5 times

Summary

This early-phase trial tests an experimental drug called LMP744 in 40 adults whose glioblastoma (a fast-growing brain cancer) has come back after standard treatment. The drug is given through a vein for 5 days in a row each month for up to a year. The goal is to see if it can shrink tumors or slow the cancer's growth. Participants will also have two surgeries: one to sample the tumor and another to remove as much of it as possible.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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