GBM
Clinical trials for GBM explained in plain language.
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Doctors test Virus-Based gene therapy to fight deadly brain tumors
Disease control Recruiting nowThis early-stage study is testing a new combination treatment for adults with aggressive brain cancer that has returned after prior therapy. After surgeons remove as much tumor as possible, a modified virus is injected into the area to target remaining cancer cells. The main goal…
Matched conditions: GBM
Phase: PHASE1 • Sponsor: Henry Ford Health System • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Helmet uses sound waves to open Brain's barrier for cancer drugs
Disease control Recruiting nowThis early-stage study is testing whether a special helmet that uses focused ultrasound can safely and temporarily open the blood-brain barrier in adults with glioblastoma. The goal is to help standard chemotherapy drugs reach the brain tumor more effectively. Researchers will en…
Matched conditions: GBM
Phase: PHASE1 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New ultrasound 'Helmet' trial aims to zap brain cancer
Disease control Recruiting nowThis study is testing if a new, non-invasive ultrasound device, used with a light-sensitive drug, can help control a fast-growing brain cancer called glioblastoma. After standard surgery and chemo-radiation, about 100 patients will be randomly assigned to receive either the real …
Matched conditions: GBM
Phase: PHASE2 • Sponsor: Alpheus Medical, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New hope for aggressive brain cancer? major trial tests promising drug
Disease control Recruiting nowThis study is testing if a drug called niraparib helps adults with a newly diagnosed, aggressive brain tumor (glioblastoma) live longer than the current standard drug, temozolomide. About 450 participants will be randomly assigned to receive one of these two drugs, taken daily al…
Matched conditions: GBM
Phase: PHASE3 • Sponsor: Ivy Brain Tumor Center • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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Precision mapping could boost brain tumor treatment effectiveness
Disease control Recruiting nowThis study is testing whether using advanced MRI techniques to create personalized maps for electrical therapy devices works better than standard mapping for glioblastoma brain tumors. Participants who are starting the Optune electrical therapy will receive either standard mappin…
Matched conditions: GBM
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC