Sound wave helmet aims to boost brain cancer treatment

NCT ID NCT07179328

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early study tests a special helmet that uses focused ultrasound to temporarily open the blood-brain barrier in people with glioblastoma. The goal is to let more chemotherapy reach the tumor. Ten adults who have already had surgery and standard chemo will receive the ultrasound treatment during their maintenance chemo. Researchers will check if it is safe and if it helps the chemo work better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Focused ultrasound device and DEFINITY® microbubbles

What this could lead to

If it works, this could make chemotherapy more effective for glioblastoma by helping it reach the tumor.

What could go wrong

This is a very small, early safety trial with only 10 people. It may not improve outcomes, and there are risks like bleeding or swelling in the brain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer brain glioblastoma glioblastoma glioma glioma susceptibility 1 pediatric high-grade glioma primary brain neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact