Sound wave helmet aims to boost brain cancer treatment

NCT ID NCT07179328

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early study tests a special helmet that uses focused ultrasound to temporarily open the blood-brain barrier in people with glioblastoma. The goal is to let more chemotherapy reach the tumor. Ten adults who have already had surgery and standard chemo will receive the ultrasound treatment during their maintenance chemo. Researchers will check if it is safe and if it helps the chemo work better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Focused ultrasound device and DEFINITY® microbubbles
What this could lead to
If it works, this could make chemotherapy more effective for glioblastoma by helping it reach the tumor.
What could go wrong
This is a very small, early safety trial with only 10 people. It may not improve outcomes, and there are risks like bleeding or swelling in the brain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.