GBM
Clinical trials for GBM explained in plain language.
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New drug combo takes aim at aggressive brain tumor
Disease control CompletedThis study tested a drug called VAL-083, given alongside standard radiation therapy, for people newly diagnosed with an aggressive brain cancer called glioblastoma (GBM). It focused on patients whose tumors have a specific genetic feature (unmethylated MGMT) that makes them less …
Matched conditions: GBM
Phase: PHASE2 • Sponsor: Kintara Therapeutics, Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Experimental brain cancer cocktail tested in first human trial
Disease control CompletedThis early-stage study tested whether combining two existing cancer drugs (pembrolizumab and vorinostat) with standard chemotherapy and radiation is safe for people newly diagnosed with glioblastoma, an aggressive brain tumor. The trial involved 21 participants to determine the h…
Matched conditions: GBM
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Scientists test new drug combo to fight deadly brain Tumor's return
Disease control CompletedThis study tested if two oral drugs, LY3214996 and abemaciclib, could reach brain tumors in people with recurrent glioblastoma. Up to 50 adults scheduled for surgery took the drugs before their operation so researchers could measure drug levels in the tumor tissue. The main goals…
Matched conditions: GBM
Phase: EARLY_PHASE1 • Sponsor: Nader Sanai • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC