GBM

This early-stage study is testing whether the drug niraparib can effectively reach brain tumors and slow their growth. It involves 42 adults with newly diagnosed glioblastoma or a specific type of recurrent brain cancer. The trial first checks if the drug gets into the tumor duri…

This early-stage study is testing whether adding an experimental drug called S-Gboxin to standard brain cancer treatment helps control aggressive tumors like glioblastoma. It will involve about 10 patients with these difficult-to-treat cancers. Researchers will monitor how patien…

This study is testing a new approach for treating glioblastoma when it returns after initial treatment. It compares a new method—using an implanted ultrasound device to temporarily open the brain's protective barrier so more chemotherapy can reach the tumor—against standard chemo…

This early-stage study is testing a new drug called ST101 in patients with advanced solid tumors that cannot be surgically removed and have spread. The trial aims to find a safe and effective dose for cancers including glioblastoma, melanoma, breast cancer, and prostate cancer in…

This early-stage study is testing whether adding a strict, high-fat ketogenic diet to standard radiation and chemotherapy is safe and feasible for adults newly diagnosed with glioblastoma, an aggressive brain cancer. For 16 weeks, participants follow personalized meal plans desig…

This study aims to see if a new type of brain scan (called DMI) can predict how well a treatment works for glioblastoma, an aggressive brain cancer. It will test the scan in patients who are also receiving an experimental drug (BPM31510) added to standard care. The main goal is t…

This study is testing whether combining a pill called niraparib with a wearable device that delivers Tumor-Treating Fields (TTFields) can help control recurrent glioblastoma, a very aggressive brain cancer. The goal is to see if the device makes the tumor cells more vulnerable to…

This early-stage trial is testing whether giving immunotherapy drugs before surgery helps the body's immune system fight recurrent glioblastoma, a fast-growing brain cancer. About 63 participants will receive either one drug, a combination of two drugs, or a placebo before their …