Immune combo tackles deadly brain tumor in early trial

NCT ID NCT04606316

First seen Feb 23, 2026 · Last updated Apr 29, 2026 · Updated 5 times

Summary

This early-phase study tests two immunotherapy drugs (nivolumab and ipilimumab) given before surgery in people with recurrent glioblastoma, an aggressive brain cancer. The goal is to see if the drugs are safe and how they affect immune cells in the tumor. About 63 participants will receive either the drug combination or a placebo before their surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Stanford University

    Stanford, California, 94305, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.