Belly tissue used to bypass brain barrier in cancer fight
NCT ID NCT04222309
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests a new surgical approach for recurrent glioblastoma, an aggressive brain cancer. After standard tumor removal, surgeons place a piece of abdominal tissue (omentum) into the brain cavity to bypass the blood-brain barrier. The study involves 10 adults and primarily checks for safety issues like infection, stroke, or rapid tumor growth over 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- omental free flap (a piece of abdominal tissue transplanted into the brain)
- What this could lead to
- If successful, this could provide a new way to deliver treatments directly to brain tumors, potentially improving outcomes for recurrent glioblastoma.
- What could go wrong
- This is a very early phase 1 trial with only 10 participants, focused on safety. The procedure is invasive and carries risks like infection, stroke, or tumor progression. It may not improve survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Lenox Hill Brain Tumor Center
New York, New York, 10075, United States
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