Can combo drugs penetrate tough brain tumors? new study seeks answers
NCT ID NCT04391595
First seen Mar 26, 2026 · Last updated Jun 12, 2026 · Updated 12 times
Summary
This study looked at whether a combination of two drugs (LY3214996 and abemaciclib) can reach brain tumors in people with recurrent glioblastoma, a type of aggressive brain cancer. About 42 participants took the drugs before surgery to remove their tumor, and researchers measured drug levels in the tumor tissue and spinal fluid. The goal was to see if the drugs penetrate the brain and potentially slow tumor growth.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Chandler Regional Medical Center
Chandler, Arizona, 85224, United States
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HonorHealth Scottsdale Osborn Medical Center
Scottsdale, Arizona, 85251, United States
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St. Joseph's Hospital and Medical Center
Phoenix, Arizona, 85013, United States
Conditions
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