Sound waves and a drug may fight brain cancer

NCT ID NCT07225621

Recruiting now Disease control Sponsor: Alpheus Medical, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests an experimental treatment for glioblastoma, a serious brain cancer. It combines a drug (5-ALA) with a special ultrasound device that aims to target cancer cells without surgery. About 103 people who have completed standard therapy will be randomly assigned to get the active treatment or a sham version. Both groups will also receive standard chemotherapy. The goal is to see if this approach helps people live longer without their cancer growing.

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Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GBM GLIOBLASTOMA

Contacts and locations

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Locations

Albany Medical Center
RECRUITING

Albany, New York, 12208, United States
Columbia University
RECRUITING

New York, New York, 10032, United States
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Dent Neurologic Institute
RECRUITING

Buffalo, New York, 14226, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
New York Langone
RECRUITING

New York, New York, 10016, United States
Northwell Health
RECRUITING

Long Island City, New York, 11030, United States
Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
Penn State Milton S. Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033, United States
University of Rochester
RECRUITING

Rochester, New York, 19642, United States

Contact Email: •••••@•••••

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