Brain zap tuning: could different electrical frequencies protect hand function during tumor surgery?

NCT ID NCT05023434

Recruiting now Knowledge-focused Sponsor: Medical College of Wisconsin Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study involves 20 people undergoing awake brain surgery for tumors near the hand movement area. Surgeons will test different electrical stimulation frequencies (10 to 250 Hz) to see which ones best identify or even improve hand movement. The goal is to develop a more precise way to map the brain during surgery, potentially reducing the risk of permanent hand weakness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Intraoperative direct electrical stimulation with varied parameters
What this could lead to: If successful, this could help surgeons better map hand movement areas during brain surgery, potentially reducing the risk of permanent hand weakness after tumor removal.
What could go wrong: This is a very small early study (20 people) focused on measurement methods, not treatment. It may not lead to any change in patient outcomes or surgical practice.

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Conditions

The condition(s) this trial relates to.

brain cancer brain neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN CANCER BRAIN TUMOR MOTOR CORTEX; LESION

Contacts and locations

Locations

Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States

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