BRAIN CANCER

This study tested a new surgical technique in 12 patients with newly diagnosed glioblastoma, an aggressive brain cancer. Surgeons placed a tissue flap from the scalp into the brain tumor cavity to bypass the blood-brain barrier, which normally blocks many treatments. The main goa…

This phase 2 trial tested a drug called VAL-083 combined with standard radiation in 29 people with newly diagnosed glioblastoma, a fast-growing brain cancer. The study focused on patients whose tumors have a specific genetic marker (unmethylated MGMT) that makes them resistant to…

This early study tested a new imaging technique that combines a special tracer ([18F]PARPi) with PET and MRI scans to get clearer pictures of brain tumors. Five adults with new or suspected returning brain tumors took part. The goal was to see how well the tracer highlights tumor…

This study tested a new MRI contrast agent called RVP-001, made with manganese instead of gadolinium, in 18 adults with known brain lesions (like tumors or multiple sclerosis). The goal was to see if it is safe and can detect lesions as well as current gadolinium-based dyes. Each…

This small study tested a virtual reality game called Hometown Bound in 9 adults with mild cognitive impairment after cancer or ICU stay. Participants played the game three times a week for four weeks. Researchers measured memory and thinking skills before and after using standar…

This study tested whether a simple walking program, guided by a fitness tracker, could help cancer patients tolerate their chemoradiotherapy without missing treatments. 166 adults with brain, head and neck, lung, gastrointestinal, or cervical cancer participated. Patients were gi…

This study tested whether a web-based tool called eSNAP, combined with a caregiver navigator, could help family caregivers of brain cancer patients feel less anxious and burdened. The tool helps caregivers map out their support network, while the navigator provides guidance. Rese…

This study tested a therapy called Managing Cancer and Living Meaningfully (CALM) to see if it helps people with brain cancer feel less distressed. 60 adults with brain tumors or brain metastases who had high depression or death anxiety took part. The study measured how many peop…

This study tested a program called ImPACT for brain cancer survivors who have trouble with thinking and memory. The program pairs each survivor with a carer to identify strengths and challenges, and create practical strategies for daily life. The trial enrolled 27 survivors and t…

This completed study enrolled over 1,200 people with brain or spinal cord tumors to collect medical information, blood samples, and tumor tissue. The goal was to better understand these cancers and identify promising areas for future research. Participants also received guidance …

This completed study enrolled 84 people with brain tumors, meningioma, or high-grade sarcoma who received proton beam therapy. Researchers analyzed tumor and blood samples to find biomarkers that might predict how well the cancer responds to treatment. The goal is to eventually h…

This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to one of these two methods or to standard care. The goal was to se…