BRAIN CANCER

This early-phase study tests a modified virus designed to attack brain tumor cells that have come back or grown despite previous treatment. About 62 adults with certain types of brain cancer will receive the virus directly into the tumor, sometimes with a drug to boost the immune…

This early-phase study tests a personalized cell therapy for people with glioblastoma, an aggressive brain cancer. The treatment uses the patient's own immune cells, which are genetically modified to better recognize and attack the tumor. The main goal is to check the safety of t…

This study tests a new drug called ST101 in people with advanced solid tumors that cannot be removed by surgery or have spread. The goal is to find a safe dose and see if the drug can shrink tumors. About 125 adults with cancers like glioblastoma, melanoma, breast, or prostate ca…

This study tests whether adding AGuIX gadolinium-based nanoparticles to standard stereotactic radiation can better control brain metastases that are at higher risk of coming back after radiation alone. About 134 adults with cancers like melanoma, lung, breast, or colorectal cance…

This study compares a new AI system, COSMO, against pathologists to see which is more accurate at diagnosing brain, lung, and kidney cancers. About 30 pathologists will review up to 300 cancer slide images, while the AI analyzes the same images independently. The goal is to deter…

This study aimed to test a robotic head holder to keep patients still during whole brain radiation therapy. The goal was to see if it could keep the head within a very small range of motion. However, the study was withdrawn before enrolling any participants.

This early-phase trial tests the immunotherapy drug pembrolizumab in 60 adults with recurrent glioblastoma, an aggressive brain cancer. The main goal is to see how the drug affects immune cells inside the tumor and to check for side effects. This study is not a cure but aims to g…

This study looks at how doctors communicate with people who have glioblastoma, a serious brain cancer, and their caregivers. Researchers want to understand how information about the cancer, test results, and treatment choices is shared. The goal is to find ways to improve these c…

This study tests a new tracer for PET scans to take pictures of brain tumors in 17 adults. The tracer is given in very small amounts to see how it spreads and leaves the body. The goal is to learn more about brain tumors, not to treat them directly.