BRAIN CANCER
Clinical trials for BRAIN CANCER explained in plain language.
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Brain cancer trial tests Immune-Boosting drug before surgery
Disease control OngoingThis early-stage study is testing whether giving the immunotherapy drug pembrolizumab before surgery can boost the immune system's attack on recurrent glioblastoma, a fast-growing brain cancer. The research involves 60 adults whose cancer has returned after initial treatment. Doc…
Matched conditions: BRAIN CANCER
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Apr 01, 2026 14:40 UTC
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New drug trial offers hope for patients with advanced cancers out of options
Disease control OngoingThis early-stage study is testing a new drug called ST101 in patients with advanced solid tumors that cannot be surgically removed and have spread. The trial aims to find a safe and effective dose for cancers including glioblastoma, melanoma, breast cancer, and prostate cancer in…
Matched conditions: BRAIN CANCER
Phase: PHASE1, PHASE2 • Sponsor: Sapience Therapeutics • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Scientists weaponize cold sore virus to fight deadly brain tumors
Disease control OngoingThis is a first-in-human safety study testing a genetically engineered virus, rQNestin34.5v.2, as a potential treatment for recurrent malignant brain tumors (gliomas). The virus is designed to infect and kill only cancer cells while sparing healthy brain tissue. The main goals ar…
Matched conditions: BRAIN CANCER
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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AI takes on doctors in High-Stakes cancer diagnosis showdown
Diagnosis ENROLLING_BY_INVITATIONThis study aims to see if an artificial intelligence (AI) system can diagnose specific types of brain, lung, and kidney cancer as accurately as human pathologists. Up to 25 experienced pathologists will review digital images of 300 patient samples, while the AI system analyzes th…
Matched conditions: BRAIN CANCER
Sponsor: Harvard Medical School (HMS and HSDM) • Aim: Diagnosis
Last updated Mar 27, 2026 12:38 UTC
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Robotic system aims to keep patients still during brain cancer treatment
Knowledge-focused TerminatedThis study aimed to develop a new robotic system to help keep patients' heads perfectly still during whole brain radiation therapy. Researchers wanted to track head movements in real time and make tiny adjustments during treatment. The goal was to improve treatment accuracy by ke…
Matched conditions: BRAIN CANCER
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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First human test of tiny particle tracer for brain cancer scans
Knowledge-focused OngoingThis is a very early study to test a new type of imaging tracer for brain tumors. Researchers are giving a tiny, safe dose of the tracer to a small group of patients and using PET scans to see how it moves through the body and collects in the tumor. The goal is to gather informat…
Matched conditions: BRAIN CANCER
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Glove-Tech aims to protect hand function in brain tumor surgery
Knowledge-focused OngoingThis study aims to improve how surgeons monitor hand function during awake brain tumor surgery. Researchers will test a special data glove and different stimulation settings to measure hand strength and movement more precisely. The goal is to help surgeons remove as much tumor as…
Matched conditions: BRAIN CANCER
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Listening to the hardest conversations: how brain cancer patients and doctors talk about the future
Knowledge-focused OngoingThis study aims to understand how doctors communicate with patients who have glioblastoma, a serious brain cancer, and their caregivers. Researchers are observing conversations about scan results, treatment options, and difficult topics like prognosis and end-of-life care. The go…
Matched conditions: BRAIN CANCER
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC