Virus therapy takes on brain cancer: early trial underway

NCT ID NCT03152318

First seen Mar 04, 2026 · Last updated Apr 28, 2026 · Updated 4 times

Summary

This early-phase study tests a modified herpes virus designed to attack brain tumor cells directly. The virus is injected into the tumor, and some participants also receive a drug to boost the immune response. The main goal is to find the safest dose and see how the body reacts. About 62 adults with recurrent malignant glioma are taking part.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Johns Hopkins University Medical Center

    Baltimore, Maryland, 21287, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.