EPENDYMOMA
Clinical trials for EPENDYMOMA explained in plain language.
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Custom immune cells take aim at childhood brain cancers
Disease control Recruiting nowThis early-phase study tests a personalized treatment for children under 5 with certain brain tumors. Doctors take a patient's own immune cells, train them to recognize unique markers from their tumor, and give them back to fight the cancer. The goal is to see if this approach is…
Matched conditions: EPENDYMOMA
Phase: PHASE1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated May 17, 2026 00:31 UTC
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Could a drug combo boost immunity against childhood brain tumors?
Disease control Recruiting nowThis study tests a new combination of drugs for children and young adults (ages 6–25) with brain cancers like medulloblastoma or glioblastoma that have come back or not responded to treatment. The goal is to find a safe dose of ibrutinib when added to an immunotherapy drug (indox…
Matched conditions: EPENDYMOMA
Phase: PHASE1 • Sponsor: Theodore S. Johnson • Aim: Disease control
Last updated May 17, 2026 00:29 UTC
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New pill takes on brain tumors: first human trial begins
Disease control Recruiting nowThis early-stage trial tests an oral drug called ONC206 in adults with brain tumors that have come back. The main goal is to find the safest dose and understand side effects. About 102 participants will receive the drug weekly or multiple days per week.
Matched conditions: EPENDYMOMA
Phase: PHASE1 • Sponsor: Jazz Pharmaceuticals • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Engineered immune cells injected directly into brain to fight childhood tumors
Disease control Recruiting nowThis early-stage trial tests a new treatment for children and young adults (up to age 21) with certain brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack a p…
Matched conditions: EPENDYMOMA
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New hope for rare tumor disorder: Multi-Drug trial launches
Disease control Recruiting nowThis study tests several experimental drugs in people with NF2-related schwannomatosis, a genetic condition that causes non-cancerous tumors in the nervous system. About 109 participants will receive one of three drug combinations to see if they can shrink tumors and control the …
Matched conditions: EPENDYMOMA
Phase: PHASE2 • Sponsor: Scott R. Plotkin, MD, PhD • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Engineered immune cells injected directly into the brain show promise for childhood cancers
Disease control Recruiting nowThis early-stage study is testing whether specially engineered immune cells (CAR T cells) can be safely given directly into the brain or spinal fluid of children and young adults with aggressive brain tumors like DIPG or recurrent medulloblastoma. The cells are designed to recogn…
Matched conditions: EPENDYMOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New proton beam approach aims to shrink Kids' brain tumors with fewer side effects
Disease control Recruiting nowThis early-stage trial tests a new type of proton therapy for children with ependymoma, a brain tumor. The treatment uses special proton beams designed to kill tumor cells while sparing healthy brain tissue. About 48 children will take part to see if the therapy is safe and to ch…
Matched conditions: EPENDYMOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New drug targets aggressive brain tumors in early trial
Disease control Recruiting nowThis study tests a drug called PLX038 in adults with brain or spinal cord tumors, especially those with changes in the MYC or MYCN genes. The goal is to see if the drug can shrink tumors or stop them from growing. Participants receive the drug through an IV every 3 weeks for up t…
Matched conditions: EPENDYMOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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Brain tumor study aims to sharpen diagnosis and treatment
Knowledge-focused Recruiting nowThis study looks at how the latest brain tumor classification system (from 2021) helps doctors better understand and treat different types of brain tumors. Researchers will collect data from 1,650 patients to see if the new system groups patients more accurately and to create tre…
Matched conditions: EPENDYMOMA
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC • Aim: Knowledge-focused
Last updated May 06, 2026 16:03 UTC
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Tailored tumor testing aims to match kids with best drugs
Knowledge-focused Recruiting nowThis study is testing a new approach for children and young adults whose medulloblastoma or ependymoma has come back. After surgery, the tumor is quickly tested in the lab and its genes are analyzed to find the most effective and least toxic drugs for that specific patient. A spe…
Matched conditions: EPENDYMOMA
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC