New drug targets aggressive brain tumors in early trial

NCT ID NCT06161519

First seen Jan 11, 2026 · Last updated May 08, 2026 · Updated 13 times

Summary

This study tests a drug called PLX038 in adults with brain or spinal cord tumors, especially those with changes in the MYC or MYCN genes. The goal is to see if the drug can shrink tumors or stop them from growing. Participants receive the drug through an IV every 3 weeks for up to 7 months, with follow-up for 5 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.