New brain tumor labels could guide better treatments

NCT ID NCT05259605

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is collecting data from 1,650 people with various brain tumors to see if the updated 2021 WHO classification system helps doctors group patients more accurately and choose better treatments. Researchers will track responses to therapy, survival, and tumor features over 5 years. The goal is to create provisional treatment guidelines for newly defined tumor types based on real-world experience.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better classify brain tumors and choose more effective treatments based on the latest diagnostic criteria.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly test new therapies. Results may take years and might not change current practice immediately.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

central nervous system melanocytic neoplasm choroid plexus neoplasm Choroid Plexus Neoplasms diffuse midline glioma, H3 K27M-mutant embryonal neoplasm ependymoma germ cell tumor glioma hemangioblastoma hemangiopericytoma mixed neuronal-glial tumor Neoplasms, Germ Cell and Embryonal pineal body neoplasm Pinealoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AZ Delta - Campus Rumbeke

    RECRUITING

    Roeselare, Belgium

  • Azienda Ospedaliero-Universitaria Careggi

    RECRUITING

    Florence, Italy

  • C.H.U. Sart-Tilman

    RECRUITING

    Liège, Belgium

  • CHU Lyon - Hopital neurologique Pierre Wertheimer

    RECRUITING

    Lyon, France

  • Centre Hospitalier Universitaire Vaudois

    RECRUITING

    Lausanne, Switzerland

  • Centro Hospitalar Universitario Lisboa Norte - Hospital Sta. Maria

    RECRUITING

    Lisbon, Portugal

  • Diagnostic & Therapeutic Center of Athens Hygeia Hospital S.A.

    RECRUITING

    Athens, Greece

  • Erasmus MC

    RECRUITING

    Rotterdam, Netherlands

  • Hopital de La Timone

    RECRUITING

    Marseille, France

  • Hopital la Pitie-Salpetriere

    RECRUITING

    Paris, France

  • Hospital Clinic de Barcelona

    RECRUITING

    Barcelona, Spain

  • Hospital De La Santa Creu I Sant Pau

    RECRUITING

    Barcelona, Spain

  • Hospital Duran i Reynals

    RECRUITING

    L'Hospitalet de Llobregat, Spain

  • Hospital Germans Trias i Pujol (Institut Catala D'Oncologia)

    RECRUITING

    Barcelona, Spain

  • IRCCS Ospedale San Raffaele

    RECRUITING

    Milan, 20132, Italy

  • IRCCS-Regina Elena National Cancer Center

    RECRUITING

    Roma, 00144, Italy

  • Innsbruck Universitaetsklinik

    RECRUITING

    Innsbruck, Austria

  • Institut Catala d'Oncologia - ICO L'Hospitalet - Hospital Duran i Reynals

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08908, Spain

  • Institut Jules Bordet

    RECRUITING

    Anderlecht, Belgium

  • Instituto Portugues de Oncologia de Lisboa Francisco Gentil - EPE

    RECRUITING

    Lisbon, Portugal

  • Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, Italy

  • Istituto Oncologico Veneto

    RECRUITING

    Padova, Italy

  • Knappschaft Krankenhaus Langendreer

    RECRUITING

    Bochum, 44892, Germany

  • Leiden University Medical Centre

    RECRUITING

    Leiden, Netherlands

  • NHS Lothian - The Royal Infirmary Of Edinburgh

    RECRUITING

    Edinburgh, EH16 4SA, United Kingdom

  • Newcastle Hospitals NHS Trust - Freeman Hospital, Northern Centre For Cancer Care

    RECRUITING

    Newcastle upon Tyne, United Kingdom

  • Nottingham University Hospitals NHS Trust - City Hospital

    RECRUITING

    Nottingham, United Kingdom

  • Onze Lieve Vrouw Ziekenhuis

    RECRUITING

    Aalst, Belgium

  • Oslo University Hospital - Radiumhospitalet

    RECRUITING

    Oslo, Norway

  • Ospedale Bellaria-Bologna

    RECRUITING

    Bologna, Italy

  • Ospedale San Giovanni - Dipartimento Neuroscienze

    RECRUITING

    Torino, Italy

  • The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis

    RECRUITING

    Amsterdam, Netherlands

  • UniversitaetsSpital Zurich - Neurology Clinic

    RECRUITING

    Zurich, Switzerland

  • Universitaetsklinikum - Essen

    RECRUITING

    Essen, 45147, Germany

  • Universitaetsklinikum Bonn

    RECRUITING

    Bonn, 53105, Germany

  • Universitaetsklinikum Jena

    RECRUITING

    Jena, 07447, Germany

  • Universitaetsklinikum Koeln

    RECRUITING

    Cologne, 50937, Germany

  • Universitaetsklinikum Leipzig-Klinik fuer Strahlentherapie und Radioonkologie

    RECRUITING

    Leipzig, Germany

  • Universitaetsklinikum Regensburg

    RECRUITING

    Regensburg, Germany

  • Universitaetsklinikum Wien - AKH unikliniken

    RECRUITING

    Vienna, Austria

  • Universitair Ziekenhuis Brussel

    RECRUITING

    Brussels, Belgium

  • University Hospital Frankfurt -Senckenberg Institute of Neurooncology

    RECRUITING

    Frankfurt, Germany