European Organisation For Research And Treatment Of Cancer - Eortc

This study tests a drug called elacestrant against standard hormone therapy in 220 people with ER+/HER2- breast cancer whose blood tests show signs of cancer returning (ctDNA) but no visible spread. The goal is to see if elacestrant can delay or prevent distant metastasis. Partic…

This phase 3 trial tests whether the drug vorasidenib can delay cancer progression in people with a specific type of brain tumor (IDH-mutant astrocytoma) after they finish standard radiation and chemotherapy. About 468 adults will receive either vorasidenib or a placebo daily. Th…

This study tests a drug called 177Lu-DOTATATE for people with recurrent meningioma, a type of brain tumor that has come back after surgery or radiation. The drug delivers radiation directly to tumor cells that have a specific marker (SSTR). About 136 adults will be randomly assig…

This study tests whether adding a precise, high-dose form of radiation (SABR) to the standard immunotherapy drug pembrolizumab can help people with head and neck cancer that has spread to only a few spots (up to 5). About 200 adults with this type of cancer will be randomly assig…

This study tests whether giving chemotherapy before surgery helps people with high-risk retroperitoneal sarcoma (a rare cancer in the abdomen) live longer without the cancer coming back. About 250 adults with specific sarcoma types will be randomly assigned to receive chemo then …

This study tests whether continuing the immunotherapy drug cemiplimab for up to a year can help people with stage IV non-small cell lung cancer that has spread to only a few spots (oligometastatic). After initial treatment with cemiplimab plus chemotherapy and targeted radiation …

This study tests whether the drug tebentafusp can prevent uveal melanoma from returning in patients at high risk after their initial treatment. About 290 participants will either receive the drug or be observed without treatment. The goal is to see if tebentafusp extends the time…

This study is for people whose glioblastoma (a type of brain cancer) has come back after initial treatment. It compares the standard chemotherapy drug lomustine alone versus lomustine plus a second round of radiation. The goal is to see if the combination helps patients live long…

This study tests whether men with advanced prostate cancer can safely take breaks from hormone therapy instead of staying on it continuously. The goal is to see if intermittent treatment works just as well for survival while reducing side effects and improving quality of life. Ab…

This study is building a large collection of tumor samples, images, and health information from nearly 5,000 cancer patients. The goal is to help researchers better understand how cancer works and find new ways to diagnose and treat it. Participants must be at least 12 years old …

This study looks at how the latest brain tumor classification system (from 2021) helps doctors better understand and treat different types of brain tumors. Researchers will collect data from 1,650 patients to see if the new system groups patients more accurately and to create tre…