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New hope for tough brain tumors: targeted radiation trial launches

NCT ID NCT06326190

Recruiting now Disease control Sponsor: European Organisation for Research and Treatment of Cancer - EORTC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called 177Lu-DOTATATE for people with recurrent meningioma, a type of brain tumor that has come back after surgery or radiation. The drug delivers radiation directly to tumor cells by targeting a protein found on these tumors. About 136 adults will be randomly assigned to receive the drug or standard care, and researchers will track how long the tumor stays under control.

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Conditions

The condition(s) this trial relates to.

meningioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECURRENT MENINGIOMA

Contacts and locations

Locations

  • A.O Landeskrankenhaus - Innsbruck Universitaetsklinik

    RECRUITING

    Innsbruck, 6020, Austria

  • Assistance Publique - Hopitaux de Marseille APHM - Hopital de La Timone (APHM)

    RECRUITING

    Marseille, 13005, France

  • CHRU de Nancy - Hopitaux De Brabois

    RECRUITING

    Vandœuvre-lès-Nancy, 54511, France

  • CHU de Lyon - CHU Lyon - Hopital neurologique Pierre Wertheimer

    RECRUITING

    Lyon, 69500, France

  • CHU de Toulouse - Institut Claudius Regaud - IUCT oncopole

    RECRUITING

    Toulouse, 31100, France

  • Centre Eugene Marquis

    RECRUITING

    Rennes, 35042, France

  • Centre Leon Berard

    RECRUITING

    Lyon, 69008, France

  • Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

  • Hospital Universitario 12 De Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Ludwig-Maximilians-Universitaet Muenchen - Campus Grosshadern

    RECRUITING

    München, 81377, Germany

  • Oncology Institute of Southern Switzerland (IOSI) - Ospedale San Giovanni

    NOT_YET_RECRUITING

    Bellinzona, 6500, Switzerland

  • Oslo University Hospital - Radiumhospitalet

    RECRUITING

    Oslo, 0379, Norway

  • St Olavs University Hospital - St. Olavs Hospital, Trondheim University Hospital

    RECRUITING

    Trondheim, 7030, Norway

  • UniversitaetsSpital Zurich - Neurology Clinic

    NOT_YET_RECRUITING

    Zurich, 8091, Switzerland

  • Universitaetskliniken der Uni Wien - Universitaetsklinikum Wien - AKH unikliniken

    RECRUITING

    Vienna, 1090, Austria

  • Universitaetsklinikum - Essen

    RECRUITING

    Essen, 45147, Germany

  • Universitaetsklinikum Heidelberg - UniversitaetsKlinikum Heidelberg - Head Hospital

    RECRUITING

    Heidelberg, 69120, Germany

  • University Frankfurt - Goethe Univ. - University Hospital Frankfurt- Klinik für Neurologie Funktionsbereich Neuroonkologie

    RECRUITING

    Frankfurt, 60590, Germany

  • Vall D Hebron - Hospital Universitari Vall d'Hebron -Vall d'Hebron Institut Oncologia

    RECRUITING

    Barcelona, 08035, Spain

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