EPENDYMOMA

This study looked at whether giving chemotherapy after surgery and radiation helps children and young adults (ages 1-21) with a newly diagnosed brain tumor called ependymoma. About 479 participants were split into groups: some got chemo after radiation, others did not. The goal w…

This early-phase study tested a new treatment for children and young adults with brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack a protein called EGFR fou…

This registry collected information and biological samples from 354 children and young adults (ages 0-21) diagnosed with certain brain tumors like medulloblastoma or ependymoma. The goal was to improve diagnosis quality by having experts review scans and lab results, and to gathe…

This study looked at how radiation therapy changes the brains and lives of children with central nervous system tumors. Researchers followed 76 kids for up to 5 years, using MRI scans, blood and urine tests, and surveys to measure memory, quality of life, and side effects. The go…

This study looked at whether it's possible to use a child's tumor DNA to choose their next treatment. 186 children with cancers that came back or didn't respond to standard therapy had their tumors analyzed. The goal was to see if this approach could be done quickly enough to gui…

This study gathered health and genetic information from 326 adults with rare central nervous system tumors. Participants completed surveys about their medical history, symptoms, and lifestyle, and provided a saliva sample for DNA analysis. The goal is to better understand what ca…